Table 2. Calculated Relative Interaction Energy of FOXC2 with Various DNA Sequences.
DNA sequence | calculated relative ΔG protein–DNA interaction (kcal/mol) |
---|---|
TAAACA (current structure) | 0.0 |
CAAACA | 0.0 |
AAAACA | 0.4 |
TGAACA | 1.0 |
TAGACA | 1.5 |
TAAGCA | 0.6 |
TAAATA | 1.5 |
TAAAAA | 6.1 |
TAAACG | –0.2 |
TAAACC | 0.0 |
TAAACT | 0.1 |
ATAACA | 0.3 |
CAAATA | 1.6 |
TACACA | 1.2 |