Table 5. Correlation between congenital syphilis case rates, death, epidemiologic, and socioeconomic variables, Brazil, 2010–2015*.
Variable | Congenital syphilis,† n = 77,414 |
Infant death,‡
n = 906 |
Fetal death,§
n = 2,877 |
Stillbirth,¶
n = 3,130 |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
r value# | p value | r value# | p value | r value# | p value | r value# | p value | ||||
Maternal syphilis | 0.688 | <0.001 | 0.535 | 0.002 | 0.563 | 0.001 | 0.301 | 0.106 | |||
Infant death | 0.679 | <0.001 | – | – | 0.439 | 0.015 | 0.523 | 0.003 | |||
Fetal death | 0.859 | <0.001 | 0.439 | 0.015 | – | – | 0.814 | <0.001 | |||
Stillbirth | 0.829 | <0.001 | 0.523 | 0.003 | 0.814 | <0.001 | – | – | |||
Maternal schooling >8 y | 0.824 | <0.001 | 0.505 | 0.004 | 0.748 | <0.001 | 0.737 | <0.001 | |||
No prenatal care | 0.305 | 0.101 | 0.132 | 0.486 | 0.360 | 0.051 | 0.613 | <0.001 | |||
Inadequate maternal treatment | 0.066 | 0.728 | 0.160 | 0.399 | 0.129 | 0.498 | 0.014 | 0.941 | |||
Untreated maternal partner | 0.066 | 0.728 | 0.342 | 0.064 | 0.012 | 0.950 | 0.040 | 0.833 | |||
Rapid syphilis test of pregnant women | 0.519 | 0.003 | 0.419 | 0.020 | 0.511 | 0.003 | 0.727 | <0.001 | |||
Illiteracy rates** | 0.476 | 0.418 | 0.430 | 0.470 | 0.251 | 0.684 | 0.348 | 0.566 | |||
Human Development Index** | 0.355 | 0.557 | 0.456 | 0.441 | 0.013 | 0.984 | 0.040 | 0.949 | |||
Gini Index** | 0.323 | 0.596 | 0.604 | 0.281 | 0.096 | 0.878 | 0.103 | 0.870 | |||
Social Vulnerability Index** | 0.467 | 0.426 | 0.627 | 0.256 | 0.172 | 0.781 | 0.193 | 0.754 |
*Bold text indicates statistically significant values (p<0.05). †Congenital syphilis rates include spontaneous abortion and stillbirth rates. ‡Death in live-born infants from birth through 12 months of age. §Fetal death at <22 weeks gestation in mothers with positive syphilis seroreactive tests. ¶Stillborn infants of >22 weeks gestation born to mothers with positive syphilis seroreactive tests. #Calculated using Pearson correlation coefficient. **Values from 2010, during the country’s last population census.