Primary cardiac undifferentiated sarcoma. (A) The tumor shows a solid growth pattern of pleomorphic cells with prominent nuclear atypia (HE, 400× magnification). (B) Only vimentin positively stains the tumor cells, whereas muscle markers (smooth muscle actin, desmin, and myogenin) and vascular markers (CD31, CD34, and factor VIII) were all negative (vimentin IHC, 400× magnification). Abbreviations: HE, hematoxylin and eosin stain; IHC, immunohistochemical stain.