Table 1.
Baseline Characteristics of the Groups
| Baseline Characteristics | Group 1, n = 14a | Group 2, n = 4b | Group 3, n = 8c | P Value |
|---|---|---|---|---|
| Age, y, no., mean ± SD (range) | 14, 45 ± 13, (25–65) | 4, 45 ± 20, (24–72) | 8, 43 ± 10, (27–62) | NS |
| Sex, n (%) | ||||
| Male | 4 (29) | 2 (50) | 1 (13) | 0.34 |
| Female | 10 (71) | 2 (50) | 7 (88) | |
| BMI, no., mean ± SD (range) | 13, 26 ± 5.3, 26 (17–37) | 4, 24 ± 4.3, (19–28) | 8, 26 ± 12, (15–55) | NS |
| Hospital admission (5 years), no., mean ± SD (range), | 11, 6.1 ± 8.3, (0–30) | 4, 12 ± 7.7, (2.0–20) | 8, 6.3 ± 4.3, (1.0–15) | NS |
| NYHA status, n (%) | ||||
| II | 10 (71) | 2 (50) | 5 (63) | 0.86 |
| III | 4 (29) | 2 (50) | 3 (38) | |
| Hydroxyurea, n (%) | ||||
| No | 8 (57) | 2 (50) | 2 (25) | 0.31 |
| Yes | 6 (43) | 2 (50) | 6 (75) |
Abbreviations: BMI, body mass index; LVEDP, Left ventricular end diastolic pressure; mPAP, Mean pulmonary artery pressure; NS, not significant; NYHA, New york heart association; PAOP, Pulmonary artery occlusion pressure; PAH, pulmonary arterial hypertension; PCWP, pulmonary capillary wedge pressure; PHTN, pulmonary hypertension; PVH, pulmonary venous hypertension; SD, standard deviation.
a
No PHTN:mPAP<25mmHg,
b
PAH:mPAP25, PAOP≥15 and LVEDP ≥ 15mmHg,
c
PVH:mPAP25 and LVEDP>15mmHg. Group 1: No pulmonary hypertension Group 2: pulmonary arterial hypertension (based on LVEDP) Group 3: pulmonary venous hypertension (based on LVEDP).