Table 4.

Discrimination of Multivariate Logistic Regression Models in Predicting 12‐Month Major Adverse Cardiac Events

Models	Discrimination
	Harrell's C Index	Net Reclassification Improvement	P Value	Integrated Discrimination Improvement	P Value
Established risk factors	0.820	Reference		Reference
Established risk factors + Hb	0.824	0.167	0.158	0.0080	0.200
Established risk factors + RDW	0.830	0.321	0.007	0.0126	0.045
Established risk factors + Hb + RDW	0.831	0.297	0.012	0.0143	0.042

Abbreviations: Hb, hemoglobin; RDW, red cell distribution width. The net reclassification improvement was defined as (P_{improved_prediction_among_patients with MACE} + P_{improved_prediction_among_patients without MACE}) − (P_{worsened_prediction_among_patients with MACE} + P_{worsened_prediction_among_patients without MACE}), where P = proportion of patients. The integrated discrimination improvement was defined as (Σⁱ _MACE (P_new(i) ‐ P_old(i))/n [patients with MACE]) ‐ (Σ^j _non‐MACE (P_new(j) ‐P_old(j))/n [patients without MACE]), where P = predicted probability of major adverse cardiac events. Established risk factors defined as sex, age >65 years, body mass index, prior coronary heart disease, hypertension, diabetes mellitus, serum creatinine, total cholesterol, percutaneous coronary intervention, antiplatelet agents, β‐blockers, and angiotensin‐converting enzyme inhibitors/angiotensin II type 1 receptor blockers use.