Table 1.
Radiosensitivity parameters, sensitivity enhancement ratio (SER) and survival fraction at 2 Gy of A549 cells irradiated with X-rays or protons in the presence or absence of inhibitors in medium with serum.
| 225 kV X-rays |
25 keV/µm protons |
||||||
|---|---|---|---|---|---|---|---|
| α (Gy−1) | β (Gy−2) | SER | SF2Gy | α (Gy−1) | SER | SF2Gy | |
| No Inh. | 0.173 ± 0.066 | 0.074± 0.002 | 0.53 | 1.238 ± 0.052 | 0.084 | ||
| Olaparib | 0.163 ± 0.004 | 0.136 ± 0.001 | 1.21 ± 0.27 | 0.42 | 1.569 ± 0.033 | 1.27 ± 0.08 | 0.043 |
| B02 | 0.234 ± 0.084 | 0.084 ± 0.022 | 1.17 ± 0.52 | 0.45 | 1.417 ± 0.018 | 1.14 ± 0.06 | 0.059 |
| B02 + Ola. | 0.313 ± 0.012 | 0.116 ± 0.003 | 1.46 ± 0.35 | 0.34 | 1.786 ± 0.054 | 1.44 ± 0.10 | 0.028 |