FIGURE 2.

Liver regeneration and hepatocyte proliferation after 70% partial hepatectomy.

(a) The rate of liver regeneration after partial hepatectomy (PH). Data are representative of at least four independent experiments (*P< .05). (b) Serum alanine aminotransferase (ALT) levels were measured in each group of three mice (*P< .05). (c) Immunostaining of PCNA before and 48 h after PH (magnification, 200×). Scale bar, 50 μm. (d) The PCNA-positive cell number was measured in each group of three mice (*P< .05). (e) Protein levels of the cell-cycle markers, cyclins D, E, and A.