Table 2.
Annual cancer cases and population- attributable fraction for suboptimal dietary intake among US adults aged 20 years or older in 2015, by cancer type
| Cancer burden by cancer type | New cancer cases No. (95% UI)* | Population- attributable fraction % (95 UI)† |
|---|---|---|
| Colon and rectum | 52 225 (49 263 to 55 302) | 38.3 (36.1 to 40.4) |
| Mouth, pharynx, and larynx | 14 421 (12 492 to 16 146) | 25.9 (22.6 to 28.9) |
| Corpus uteri | 3165 (2590 to 3406) | 6.08 (5.67 to 6.53) |
| Breast (postmenopausal) | 3059 (2786 to 3335) | 1.57 (1.43 to 1.71) |
| Kidney | 2017 (1907 to 2132) | 3.37 (3.19 to 3.55) |
| Stomach | 1564 (1179 to 1922) | 6.82 (5.20 to 8.43) |
| Liver | 1000 (924 to 1080) | 3.29 (3.06 to 3.58) |
| Pancreas | 538 (491 to 583) | 1.19 (1.09 to 1.30) |
| Esophagus (adenocarcinoma) | 475 (431 to 527) | 4.62 (4.23 to 5.07) |
| Thyroid | 415 (374 to 460) | 0.88 (0.80 to 0.97) |
| Prostate (advanced) | 274 (215 to 335) | 0.92 (0.72 to 1.13) |
| Multiple myeloma | 240 (214 to 270) | 1.10 (0.98 to 1.23) |
| Ovary | 173 (146 to 199) | 0.84 (0.71 to 0.97) |
| Gallbladder | 105 (95 to 117) | 2.81 (2.59 to 3.07) |
| Total | 80 110 (76 316 to 83 657) | 5.23 (4.98 to 5.46) |
For each cancer type, the total number of cancer incidence attributable to poor diet = the total number of specific cancer incidence × PAF. Cancer incidence that occurred in the US adult population in 2015 were used in the above calculations. PAF = population-attributable fraction; UI = uncertainty Intervals.
For each cancer type, the PAF was estimated using the joint PAF for all dietary factors included in this analysis (fruits, nonstarchy vegetables, whole grains, processed meats, red meats, total dairy products, and sugar sweetened beverages). Joint PAF = 1 - (1-PAF dietary target1) × (1-PAF dietary target2) ×…× (1-PAF dietary targetn). Because of the overlap between the effects of different factors, the joint PAF for all dietary factors combined is less than the sum of the PAFs associated with each dietary target.