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. 2018 Dec 11;2(4):pky059. doi: 10.1093/jncics/pky059

Table 1.

The association between clinical trial characteristic and median number of excluded chronic conditions (N = 58 trials)

Clinical trial characteristic Median number of excluded conditions (IQR)* P
Eligible sex .03
 Women, only (41 trials) 2 (1–6)
 Men and women (17 trials) 0 (0–3)
Eligible age groups .59
 Adults and seniors, 18 y or older (43 trials) 2 (0–6)
 Children, adults, and seniors of all ages (10 trials) 0.5 (0–4)
 Adult, only, 18–64 y (5 trials) 3 (1–5)
Study type <.001
 Treatment (30 trials) 3.5 (2–6)
 Supportive care (23 trials) 1 (0–2)
 Prevention (5 trials) 0 (0–4)
Overall (58 trials) 2 (0–5) N/A

*Conditions were adapted from the list of the most impactful chronic conditions compiled by a multiple chronic conditions working group at the Office of the Assistant Secretary of Health (12). IQR = interquartile range.