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. 2019 Jun 5;47(13):6885–6899. doi: 10.1093/nar/gkz494

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Global structure analysis of the mgtA RNA aptamer with divalent metal ions. (A) Scattering profiles collected at separate RNA concentrations 0.8, 1.6 and 3.2 mg/ml with indicated metal, then merged. (B) Dimensionless Kratky plots. (C) Pair-wise distance distribution plots for all RNAs. (D) Simulated 3D structure of the RNA aptamer by SimRNA embedded in the envelope obtained from SAXS in the presence of Mn²⁺. SAXS simulated envelope models for WT RNA with Ca²⁺ (E), Mg²⁺ (F) and the G16A/G17A mutant RNA that is unable to bind metal (G).