Table 2.

Summary of parameters and distributions used in simulations

Parameter	Distribution
Accrual rate	Year 1: 5000
	Year 2: 25 000
	Year 3: 20 000
	Year 4: 15 000
Randomization	1: 1
Proportion in each risk strata	Low risk: 28.9
	Average risk: 40.4%
	Elevated risk: 28.2%
	High risk: 2.5%
Annual hazard for mammogram detected cancer	Low risk: 0.0198
	Average risk: 0.0414
	Elevated risk: 0.0774
	High risk: 0.2808
Median time from mammogram to clinically detectable cancer	18 months
Noncompliance time	Normal+ (0, 4 months)
Mammographic sensitivity	100%
	(Low risk: 93%
	Average risk: 86%
	Elevated risk: 76%
	High risk: 86%
	used in sensitivity analyses)
Percent with prevalent stage IIB	0.05%
Total trial time	4.5 y