Figure 1.

Flowchart of the selection of patients for the current analyses. *One participating patient revoked informed consent. ^†No CT scans available from nine participating hospitals because of logistic reasons. ^‡CT scan at start of initial therapy nonevaluable. Reasons: no CT abdomen available, incomplete depiction of skeletal muscle at L3, stoma through muscle layer at L3, scan of insufficient quality. ^§CT scan at randomization nonevaluable. Reasons: no CT abdomen available, incomplete depiction of skeletal muscle at L3, stoma through muscle layer at L3, scan of insufficient quality. CAIRO3 = Maintenance Treatment Versus Observation After Induction in Advanced Colorectal Carcinoma; CT = computed tomography.