Table 1. Characteristics of all patients and comparison of demographic, clinical and laboratory parameters inter group.
| n | All | Progressor n = 193 | Non progressor n = 147 | p | |
|---|---|---|---|---|---|
| Age (years) | 340 | 73 (69–79) | 72 (69–78) | 76 (69–80) | 0.02 |
| Male n (%) | 340 | 191 (56) | 105 (54) | 86 (58) | 0.45 |
| Caucasian n (%) | 298 | 194 (65) | 114 (67) | 80 (62) | 0.34 |
| Etiology n (%) | 340 | 0.04 | |||
| Hypertension | 63 (19) | 29 (15) | 34 (24) | ||
| Diabetes mellitus | 94 (28) | 62(32) | 32 (22) | ||
| Others | 183 (54) | 102 (53) | 81 (55) | ||
| iACE/ARB use(%)a | 340 | 227 (67) | 135 (70) | 92 (62) | 0.15 |
| Body mass index (Kg/m2) | 238 | 27.1 (24.2–30.4) | 27.0 (24.0–30.4) | 27.4 (24.6–30.0) | 0.98 |
| Systolic Blood Pressure (mmHg) | 339 | 140 (130–160) | 140 (130–160) | 140 (120–150) | 0.12 |
| Diastolic Blood Pressure (mmHg) | 339 | 80 (80–90) | 80 (80–90) | 80 (72–90) | 0.07 |
| Creatinine (mg/dL) | 340 | 1.94 (1.60–2.57) | 1.92 (1.52–2.58) | 2.00 (1.67–2.46) | 0.13 |
| Ureia (mg/dL) | 319 | 80 (63–106) | 79 (62–102) | 80 (64–108) | 0.85 |
| Proteinuria (g/L) | 286 | 0.00 (0.00–0.50) | 0.10 (0.00–0.90) | 0.00 (0.00–0.30) | 0.007 |
| Sodium (mmol/L) | 295 | 140 (138–142) | 140 (138–142) | 140 (138–142) | 0.31 |
| Potassium (mmol/L) | 314 | 4.8 (4.4–5.2) | 4.8 (4.4–5.3) | 4.7 (4.4–5.2) | 0.27 |
| Hemoglobin (g/dL) | 299 | 12.4 ±2.0 | 12.4 ± 2.0 | 12.4 ± 2.1 | 0.88 |
| Ionic Calcium (mmol/L) | 130 | 1.27 ± 0.08 | 1.28 ± 0.08 | 1.26 ± 0.09 | 0.35 |
| Phosphorus (mg/dL) | 180 | 3.7 (3.2–4.1) | 3.8 (3.3–4.1) | 3.5 (2.9–4.1) | 0.04 |
| Parathyroid hormone (pg/mL) | 71 | 124 (79–197) | 133 (94–189) | 95 (53–226) | 0.28 |
| Bicarbonate (mmol/L) | 129 | 25.17 ± 3.63 | 25.44 ± 3.33 | 24.84 ± 3.98 | 0.35 |
| Fasting plasma glucose (mg/dL) | 269 | 104 (91–120) | 104 (90–122) | 105 (97–114) | 0.74 |
| Glycated hemoglobin (A1C) (%)b | 142 | 7.1 (6.4–8.4) | 7.4 (6.4–8.6) | 7.0 (6.4–8.3) | 0.34 |
| LDL cholesterol (mg/dL) | 278 | 104 (81–130) | 105 (81–135) | 103 (81–122) | 0.52 |
| HDL cholesterol (mg/dL) | 227 | 44 (35–55) | 44 (35–55) | 43 (35–55) | 0.76 |
| Triglycerides (mg/dL) | 224 | 132 (94–177) | 139 (93–192) | 129 (95–173) | 0.51 |
| Uric acid (mg/dL) | 88 | 7.6 ± 1.82 | 7.7 ± 1.54 | 7.6 ± 2.14 | 0.71 |
a—angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers
b- only diabetes patients