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. 2019 Jul 23;14(7):e0219962. doi: 10.1371/journal.pone.0219962

Table 1. Demographic and clinical characteristics of study participants.

Descriptives
n 15
Age, mean (sd) 65.20 (4.51)
Gender, Male (%) 14 (93.3)
BMI, mean (sd) 27.65 (5.98)
Race, Caucasian/White (%) 14 (93.3)
COPD Severity, n (%)a
 Mild [FEV1pp ≥ 80%] 5 (33.3)a
 Moderate [FEV1pp = 50–79%] 7 (46.6)
 Severe [FEV1pp 30–49%] 2 (13.3)
ICS Use, Yes (%) 2 (13.3)
Pack years of smoking, mean (sd) 49.13 (19.6)
Current tobacco use, Yes (%) 3 (20.0)
Diabetes, Yes (%) 1 (6.7)
Edentulous, n (%) 3 (20.0)
Current alcohol use, Yes (%) 9 (60.0)
Gastroesophageal reflux disease, Yes (%) 7 (46.7)
Proton pump inhibitor use, Yes (%) 4 (26.7)
Oral steroid or antibiotic use in last 1 month, Yes (%) 0 (0)
Last dental visit, less than or equal to 6 months (%) 8 (53.3)
Lung cancer, n (%) 14 (93.3)
 Adenocarcinoma, n (%)b 6 (40.0)b
 Squamous Cell Carcinoma, n (%)b 8 (53.3)b
 Large Cell Neuroendocrine tumor, n (%) 1 (6.7)
 Unknown, n (%)c 1 (6.7)c

aOne subject did not have COPD by lung function criteria.

bSubject 12 had 3 lung tumors (2 adenocarcinomas, 1 squamous cell carcinoma), which are included here individually; 16 independent lung tumors were diagnosed in 14 subjects.

cOne surgery was cancelled for clinical reasons and no tissue diagnosis was made.