Table 2.

Statistically significant differences between susceptible and resistant strains

	Crystal violet assay
	MRSA vs MSSA		P. aeruginosa R vs S
	Prevention of biofilm formation	Treatment of pre-formed biofilm	Prevention of biofilm formation	Treatment of pre-formed biofilm
CQ ½ MIC	p<0.005	p<0.01	-	p<0.001
CQ ¼ MIC	p<0.01	p<0.01	-	p<0.001
GEN ½ MIC	-	-	-	-
GEN ¼ MIC	-	-	-	p<0.005
FA ½ MIC	-	-
FA ¼ MIC	-	-
	CLSM assay
	MRSA vs MSSA		P. aeruginosa R vs S
	Prevention of biofilm formation	Treatment of pre-formed biofilm	Prevention of biofilm formation	Treatment of pre-formed biofilm
CQ ½ MIC	p<0.01	p<0.01	p<0,001	p<0.001
CQ ¼ MIC	p<0.01	-	-	p<0.005
GEN ½ MIC	-	-	-	-
GEN ¼ MIC	-	-	-	-
FA ½ MIC	-	-
FA ¼ MIC	-	-

Notes: S, P. aeruginosa susceptible to carbapenems, R, P. aeruginosa resistant to carbapenems.

Abbreviations: CLSM, Confocal laser scanning microscopy; CQ, chlorquinaldol; GEN, gentamicin; FA, fusidic acid; MRSA, methicillin resistant Staphylococcus aureus; MSSA, methicillin susceptible Staphylococcus aureus.