Table 3.
Control | CQ ½ MIC | CQ ¼ MIC | GEN ½ MIC | GEN ¼ MIC | FA ½ MIC | FA ¼ MIC | ||
---|---|---|---|---|---|---|---|---|
S. aureus | ||||||||
Treatment of biofilm formation | S | 5.12 | 13.47 | 10.60 | 25.28 | 14.51 | 2.95 | 3.01 |
R | 10.48 | 25.37 | 19.49 | 7.88 | 7.64 | 7.02 | 9.61 | |
Treatment of pre-formed biofilm | S | 10.08 | 7.67 | 6.38 | 19.71 | 21.64 | 13.28 | 15.42 |
R | 6.29 | 11.54 | 19.79 | 9.87 | 9.98 | 9.85 | 6.29 | |
P. aeruginosa | ||||||||
Treatment of biofilm formation | S | 9.67 | 18.94 | 17.49 | 9.23 | 6.73 | ||
R | 4.36 | 15.49 | 20.94 | 3.35 | 1.51 | |||
Treatment of pre-formed biofilm | S | 3.35 | 7.18 | 10.21 | 12.35 | 5.52 | ||
R | 1.56 | 9.69 | 7.20 | 2.77 | 8.00 |
Notes: Data are expressed in percentage on the total biofilm biomass. S, methicillin susceptible S. aureus or carbapenems susceptible P. aeruginosa, R, methicillin resistant S. aureus or carbapenems resistant P. aeruginosa.
Abbreviations: CQ, chlorquinaldol; GEN, gentamicin; FA, fusidic acid.