Table 1.
Selected Baseline Characteristics of Propensity Score–Matched Statin Users and Nonusers From the General Cohort.a
| Statin User | |||
|---|---|---|---|
| Variable | No (%), n = 6342 | Yes (%), n = 6342 | P Value |
| Age in years: mean ± SD | 56.0 ± 12.0 | 55.7 ± 12.4 | 0.1 |
| Women | 2856 (45.0) | 2924 (46.1) | 0.2 |
| Alcohol-related disorders | 83 (1.3) | 78 (1.2) | 0.7 |
| Substance-related disorders | 24 (0.4) | 22 (0.3) | 0.8 |
| Smokerb | 534 (8.4) | 509 (8.0) | 0.4 |
| Hypertension | 3766 (59.4) | 3707 (58.5) | 0.3 |
| Dysrhythmia | 874 (13.8) | 887 (14.0) | 0.8 |
| Cerebrovascular disease | 128 (2.0) | 125 (2.0) | 0.9 |
| Peripheral and visceral atherosclerosis | 153 (2.4) | 169 (2.7) | 0.4 |
| Aortic, peripheral, and visceral artery aneurysms | 39 (0.6) | 54 (0.9) | 0.1 |
| Charlson comorbidity indexc: mean ± SD | 0.64 ± 1.23 | 0.66 ± 1.25 | 0.3 |
| Health care use at baseline | |||
| Number of inpatient admissions during baseline period | 0.25 ± 0.75 | 0.26 ± 0.77 | 0.8 |
| Number of outpatient medical encounters during baseline period | 31.67 ± 36.76 | 31.81 ± 40.63 | 0.8 |
| Medications at baseline | |||
| β-Blocker | 1099 (17.3) | 1123 (17.7) | 0.6 |
| Calcium channel blocker | 987 (15.6) | 1001 (15.8) | 0.8 |
| Aspirin | 1835 (28.9) | 1890 (29.8) | 0.3 |
| Nonsteroidal anti-inflammatory drug | 3729 (58.8) | 3702 (58.4) | 0.6 |
| Selective serotonin reuptake inhibitor | 1059 (16.7) | 1067 (16.8) | 0.9 |
| Parameters not included at propensity score matching | |||
| Epilepsy during baseline period | 61 (1.0) | 40 (0.6) | 0.4 |
a
Complete results of all variables included were previously published.17 Diagnosis groups are defined as per the Agency of Health Research and Quality-Clinical Classification Software, except if otherwise specified.
b
Diagnosis was defined as ICD-9-CM codes 3051 and V1582.
c
The Charlson comorbidity index was calculated using the Deyo et al method.23