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. Author manuscript; available in PMC: 2019 Jul 23.
Published in final edited form as: Ann Pharmacother. 2018 Feb 3;52(6):546–553. doi: 10.1177/1060028018756650

Table 3.

Risk of Epilepsy in Statin Users and Nonusers.

Statin User
Variable No (%) Yes (%) OR 95% CI P Value
Primary analyses
PS-matched general cohort: 6342 nonusers and 6342 statin users 141 (2.2) 114 (1.8) 0.91a
0.91b
0.81c
0.67–1.23
0.67–1.22
0.63–1.03
0.54
0.52
0.09
PS-matched healthy cohort: 3351 nonusers and 3351 statin users 46 (1.4) 37 (1.1) 1.08a
1.08b
0.80c
0.64–1.83
0.64–1.82
0.52–1.24
0.76
0.78
0.32
Secondary analyses
General cohort: 29 812 nonusers and 13 626 statin users 443 (1.5) 327 (2.4) 0.97a 0.75–1.25 0.78
Healthy cohort: 21 987 nonusers and 3982 statin users 246 (1.1) 43 (1.1) 0.94a 0.60–1.48 0.80
Epilepsy-incident general cohort: 29 602 nonusers and 13 517 statin users 261 (0.9) 240 (1.8) 0.99d 0.76–1.29 0.95
Epilepsy-incident healthy cohort: 21 885 nonusers and 3917 statin users 150 (0.7) 33 (0.8) 0.88d 0.61–1.52 0.97

Abbreviations: OR, odds ratio; PS, propensity score.

a

Adjusted OR: adjusting for epilepsy at baseline and propensity score.

b

Adjusted odds ratio: adjusting for epilepsy at baseline.

c

Unadjusted odds ratio using conditional logistic regression analysis.

d

Adjusted OR: adjusting for propensity score.