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. Author manuscript; available in PMC: 2019 Jul 23.
Published in final edited form as: Comput Toxicol. 2018;7:58–67. doi: 10.1016/j.comtox.2018.07.002

Table 2.

Results of filtering the dataset based on structures to categorize substances for application of structural category-specific TTC values.

TTC category Number of chemicals
Total dataset 7968
Dataset with available structures 7699
TTC is not appropriate 904
TTC is appropriate * 6795
Substances with structural alerts for genotoxicity 1853
AChEIs 102
Cramer class III 3214
Cramer class II 332
Cramer class I 1294
*

Appropriate indicates that these substances nominally fall within the “applicability domain” or “scope” of the TTC approach