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. 2019 Jul 2;6(5-6):317–336. doi: 10.18632/oncoscience.482

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Copyright: © 2019 Alwhaibi et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) Oncoprint showing genomic alterations in the Akt pathway genes in human non-metastatic prostate adenocarcinoma tissues based on the exome sequencing performed by the Broad/Cornell study (Barbieri CE et al, Nat Gen, 2012). (B) A plot showing the relationship between Akt1 mRNA abundance and copy-number alteration (CAN) in the Akt1 gene in human non-metastatic prostate adenocarcinoma. (C) Chart showing the mean mRNA expression of Akt1, Akt2, and Akt3 in the non-metastatic prostatic adenocarcinoma tissues with observed Akt pathway alterations compared to the un-altered group.