Scheme 10.
Methods used for the preparation of 18. Reagents and conditions a) 2-phenethyl-4-phenylbutanoic acid, EDC, HOBT, 2,6-lutidine; b) TFA, CH2Cl2; c) 1,3-diboc-2-(trifluoromethylsulfonyl)guanidine, Et3N, DCM (29%); d) TFA, DCM (100%)
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.