Table 1:
Th17 2D2 cell passive transfer of EAE into RAG−/− recipients is reduced in absence of BACE1. Data pooled from 4 independent experiments.
WT 2D2 | BACE1−/− 2D2 | P value (Fishers) | |
---|---|---|---|
Number of recipients | 13 | 16 | |
Incidence | 13 (100%) | 9 (56%) | 0.0084 (**) |
Death | 3 (23%) | 0 (0%) | 0.0783 |