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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Invest Dermatol. 2019 Feb 16;139(8):1753–1761.e4. doi: 10.1016/j.jid.2019.02.006

Fig 2. Intradermal injection of S. aureus LTA induces epidermal thickening and hyperproliferation.

Fig 2.

Mice were injected ID with PBS or LTA. Skin samples at site of injection were harvested 48 hours later. (a) Representative H&E staining of skin showing epidermal thickening upon LTA treatment. Bar = 100 μM. (b) Increased numbers of Ki67+ cells in the epidermis following LTA treatment. Bar = 40 μM. Dashed line represents epidermal-dermal junction. (c) Increased numbers of Keratin 5 (K5) positive cells after LTA treatment indicates keratinocyte involvement in epidermal thickening. (d) Quantitative analysis of Ki67+ cells in the epidermis. Data are mean ± SEM, n = 6, ***P<0.001.