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. 2019 Jul 23;9:10609. doi: 10.1038/s41598-019-47177-6

Table 1.

IC50 and EC50 value (in µM of Les-236) for resazurin reduction assay, caspase-3 activity assay and LDH release assay after 48 h.

assay IC50 (µM)
BJ CACO-2 SCC-15 A549 SH-SY5Y
resazurine

48.34c

(±2.07)

12.71b

(±1.06)

64.23d

(±5.10)

2062.00e

(±16.02)

0.24a

(±0.02)

assay EC50 (µM)
LDH

5.59b

(±0.04)

nd nd nd

0.37a

(±0.04)

caspase-3

29.52b

(±2.14)

10.36a

(±1.54)

nd nd

12.93a

(±1.82)

Different lower case letters for each assay indicate significant differences (p < 0.05). nd – not detected.