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. 2019 Jul 23;9:10661. doi: 10.1038/s41598-019-46996-x

Table 2.

Between-subject variability for multiparametric MRI measures in healthy participants.

Parameter Sex Group P Age Group P Mean/Total
female male age <40 age ≥40
RCT (cm) Axial 0.458 ± 0.041 0.488 ± 0.040 0.044§ 0.481 ± 0.48 0.461 ± 0.33 0.191 0.473 ± 0.0428
coronal 0.525 ± 0.028 0.571 ± 0.037 <0.001§ 0.558 ± 0.04 0.533 ± 0.03 0.085 0.547 ± 0.040
PT (cm) Axial 1.436 ± 0.077 1.485 ± 0.055 0.045§ 1.482 ± 0.06 1.43 ± 0.07 0.035§ 1.46 ± 0.071
coronal 1.687 ± 0.066 1.713 ± 0.065 0.268 1.726 ± 0.06 1.664 ± 0.06 0.006§ 1.699 ± 0.07
CPR Axial 0.321 ± 0.022 0.331 ± 0.023 0.229 0.327 ± 0.024 0.325 ± 0.021 0.869 0.326 ± 0.02
coronal 0.312 ± 0.009 0.334 ± 0.018 <0.001§ 0.323 ± 0.02 0.321 ± 0.015 0.73 0.323 ± 0.02
RCT (cm) Average 0.492 ± 0.032 0.529 ± 0.034 0.003§ 0.519 ± 0.04 0.498 ± 0.03 0.1 0.510 ± 0.04
PT (cm) 1.562 ± 0.062 1.599 ± 0.053 0.074 1.604 ± 0.05 1.547 ± 0.06 0.005§ 1.580 ± 0.05
CPR 0.317 ± 0.013 0.332 ± 0.018 0.007§ 0.325 ± 0.02 0.323 ± 0.01 0.765 0.324 ± 0.02
Average RCT/BMI 0.023 ± 0.003 0.024 ± 0.003 0.253 0.024 ± 0.003 0.023 ± 0.003 0.124 0.024 ± 0.003
Average PT/BMI 0.073 ± 0.007 0.073 ± 0.007 0.966 0.075 ± 0.007 0.071 ± 0.007 0.065 0.073 ± 0.007
R2* (s−1) cortex 17.62 ± 0.84 18.34 ± 0.90 0.024§ 17.53 ± 0.58 18.57 ± 0.99 0.001§ 17.97 ± 0.93
medulla 36.33 ± 2.81 38.09 ± 2.54 0.069 36.45 ± 2.47 38.18 ± 2.96 0.077 37.18 ± 2.78#

ADC

(x 10−3 mm2/s)

cortex 2.212 ± 0.16 2.229 ± 0.096 0.712 2.204 ± 0.17 2.243 ± 0.067 0.406 2.220 ± 0.13
medulla 2.012 ± 0.14 2.019 ± 0.11 0.873 2.047 ± 0.14 1.974 ± 0.11 0.113 2.016 ± 0.13#
FA cortex 0.203 ± 0.02 0.212 ± 0.019 0.171 0.210 ± 0.02 0.204 ± 0.02 0.421 0.207 ± 0.02
medulla 0.359 ± 0.03 0.360 ± 0.04 0.909 0.371 ± 0.03 0.343 ± 0.03 0.016§ 0.359 ± 0.03#

RCT: Renal cortical thickness; PT: Parenchymal thickness; CPR: Ratio of cortex to parenchyma; BMI: Body mass index.

§p < 0.05.

<0.001 compared to the axial by independent sample t-test.

#<0.001 compared to the cortex by independent sample t-test.