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. 2019 Jul 23;9:10689. doi: 10.1038/s41598-019-47069-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Increased replication of primary HIV-1 CRF02_AG isolates in human PBMC and MDM, compared to clade-B viruses. Reverse transcriptase activity in primary human PBMC (A–D) and MDM (E,F) infected with AG and clade-B viruses. RT activity assessed at day-12 (A,B) and day-15 (C,D) p.i. in PBMC, and from day-5 to day-18 p.i. in MDM (E,F). ^#P < 0.0001. Errors bars represent SEM.