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. 2019 Jul 17;11:181. doi: 10.3389/fnagi.2019.00181

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Copyright © 2019 Li, Chen, Zhang, Gao, Wang, Chen, Zhang, Mao, Leblanc, Behensky, Zhang, Gan, Yu, Zhu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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KEGG pathway enrichment analysis is a functional analysis for mRNAs. The P-value (EASE-score, Fisher-P-value or Hypergeometric-P-value) indicates the significance of the pathway correlated to the conditions. The lower the P-value, the more significant the pathway is (The recommended P-value cut-off is 0.05). (A) Pathways involved in up-regulated transcripts. (B) Pathways involved in down-regulated transcripts.