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. 2019 Aug;7(8):665–676. doi: 10.1016/S2213-2600(19)30086-4

Figure 2.

Figure 2

Shedding of strains in the nasopharynx after vaccination

(A) Percentage of children shedding vaccine virus with 2016–17 LAIV formulation compared with the 2017–18 LAIV formulation, at day 2 and day 7. Error bars represent the upper 95% CI. (B) Viral load in the nasopharynx is indicated by ct values from RT-PCR. Red bars indicate median ct values. Lower ct values indicate higher viral loads. (C) Quantitative RT-PCR viral load in children from the 2018 cohort for each strain. Red bars indicate median values. p values are Bonferroni-adjusted for multiplicity within each group of analyses. LAIV=live attenuated influenza vaccine. pH1N1=pandemic H1N1. H3N2=A/17/Hong Kong/2014/8296. B/Vic=B/Texas/02/2013 (Victoria lineage). ct=cycle threshold. RT-PCR=reverse-transcriptase PCR. EID50eq=50% egg infectious dose equivalents.