Table 1.
Quantitative peptides of ABC efflux transporters and their isotope internal standards.
| Transporter ID | Peptide | Q1 Mass (Da) | Q3 Mass (Da) | IS Peptide* | Q1 Mass (Da) | Q3 Mass (Da) |
|---|---|---|---|---|---|---|
| BCRP | SSLLDVLAAR | 522.9 | 644.3 | SSLLDVLAAR* | 527.9 | 654.3 |
| 522.9 | 757.3 | 527.9 | 767.3 | |||
| 522.9 | 870.3 | 527.9 | 880.3 | |||
| P-gp-MDR1 | AGAVAEEVLAAIR | 635.3 | 971.4 | AGAVAEEVLAAIR* | 640.3 | 981.4 |
| 635.3 | 900.3 | 640.3 | 910.3 | |||
| 635.3 | 771.3 | 640.3 | 781.3 | |||
| MRP2 | LTIIPQDPILFSGSLR | 885.8 | 665.5 | LTIIPQDPILFSGSLR* | 889.8 | 669.5 |
| 885.8 | 989.4 | 889.8 | 997.5 | |||
| 885.8 | 441.2 | 889.8 | 445.2 | |||
| MRP3 | IDGLNVADIGLHDLR | 541.2 | 697.1 | IDGLNVADIGLHDLR* | 544.2 | 701.1 |
| 541.2 | 754.7 | 544.2 | 759.3 | |||
| 541.2 | 288.3 | 544.2 | 292.4 | |||
| MRP4 | APVLFFDR | 482.9 | 796.5 | APVLFFDR* | 487.9 | 806.5 |
| 482.9 | 697.5 | 487.9 | 707.5 | |||
| 482.9 | 584.3 | 487.9 | 594.3 |
*Labeled amino acid.