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Affinity of LFA-1 I domain variants to human and mouse ICAM-1.
| Name | Affinity |
|---|---|
| F292A to hCD54 | 20 μM (SPR) |
| F292A to hCD54 | 12 μM (Competition assay) |
| F292A to mCD54 | 14 μM (Competition assay) |
| K287C/K294C to hCD54 | 185 nM (SPR) |
| K287C/K294C to mCD54 | 191 nM (SPR) |
| F265S/F292G to hCD54 | 6 nM (SPR) |
| F265S/F292G to mCD54 | 2 nM (SPR) |
