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. Author manuscript; available in PMC: 2019 Dec 26.
Published in final edited form as: Chem Rev. 2018 Oct 3;118(24):11519–11574. doi: 10.1021/acs.chemrev.8b00038

Figure 17.

Figure 17

Protein DNA Assemblies. (a) Structure of DNA binding domain and operator DNA (Osym). (b) Wild-type operator DNA (O1) and auxiliary operators O2 and O3. O1, O2, O3, and Osym all assemble with wild-type the DNA binding domain D1. Variations of operator DNA (OS2, OS3, OS4, and OS5) assemble with orthogonal DNA binding domains (DS2, DS3, DS4, and DS5).