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. Author manuscript; available in PMC: 2019 Dec 26.
Published in final edited form as: Chem Rev. 2018 Oct 3;118(24):11519–11574. doi: 10.1021/acs.chemrev.8b00038

Scheme 1.

Scheme 1

The Finke-Watzky mechanism of nucleation followed by autocatalytic growth [35]. A is the unassembled free peptide, which nucleates into the assembled peptide B with rate constant kn. The unassembled A may also undergo autocatalytic reaction (ke) to produce the assembled