Table 6.
Examples of algorithms for amyloid prediction
| Algorithm | Principle of analysis | Website/server |
|---|---|---|
| Waltz | Presence of hexapeptides with amyloidogenic structures | http://waltz.switchlab.org |
| AGGRESCAN | Search for 5–11 aa amyloidogenic stretches, based on aa composition | http://bioinf.uab.es/aggrescan/ |
| FoldAmyloid | Scanning for 5 aa windows, based on certain chemical properties | http://bioinfo.protres.ru/fold-amyloid/oga.cgi |
| AmylPred | Lack of stable secondary structure, combined aa composition patterns | http://biophysics.biol.uoa.gr/AMYLPRED/ |
| TANGO | β-structure forming propensity and charge | http://tango.crg.es/ |
| SARP | Aa sequences with strong compositional biases | N/A |
| ArchCandy | High propensity of β-arc formation | https://omictools.com/archcandy-tool |