. 2019 Jul 2;24(13):2425. doi: 10.3390/molecules24132425

Table 4.

Selectivity evaluation of representative compounds in SFC.

Column Name	Stationary Phase (Abbreviation)	k (SFC)						(1)	(2)	(3)	(4)
Column Name	Stationary Phase (Abbreviation)	Solute 7	Solute 8	Solute 9	Solute 10	Solute 11	Solute 12	Hydrophilic Interaction	Hydrophobic Interaction	π-π Interaction	Dispersion Interaction
COSMOSIL 5SL-II	Silica gel (SL)	0.00	1.06	10.42	1.16	1.85	1.24	9.83	1.09	1.74	1.17
COSMOSIL 5Diol-120-II	Diol Group (Diol)	0.00	1.50	15.82	1.14	4.46	0.90	10.56	0.76	2.98	0.60
COSMOSIL 5HILIC	Triazolyl group (TRZ)	0.00	1.76	23.23	1.65	4.29	1.29	13.22	0.94	2.44	0.74
COSMOSIL 5HP	Hydroxyphenyl group (HP)	0.00	1.31	13.52	1.40	2.98	1.17	10.33	1.07	2.28	0.90
COSMOSIL 5PY	Pyridinyl group (PY)	0.00	1.10	8.46	1.06	2.83	0.69	7.70	0.96	2.58	0.63
Prototype EP	Pyridinylethyl group (EP)	0.00	0.91	5.51	0.92	2.08	0.52	6.08	1.02	2.30	0.57
Prototype PIC	Picolylamine (PIC)	0.00	1.80	21.30	1.61	5.40	1.16	11.82	0.89	3.00	0.65
Prototype ANT	Aminoanthracene (ANT)	0.00	1.24	12.15	1.14	3.19	0.94	9.81	0.92	2.57	0.76
Prototype DEA	Diethylamine (DEA)	0.00	2.06	28.10	1.56	5.93	0.90	13.65	0.76	2.88	0.44
COSMOSIL 5PE-MS	Phenylethyl group (PE)	0.02	0.19	0.54	0.26	0.48	0.23	2.81	1.36	2.51	1.21
COSMOSIL 5πNAP	Naphthylethyl group (NAP)	0.00	0.31	0.85	0.45	0.95	0.41	2.79	1.46	3.10	1.34
COSMOSIL 5PYE	Pyrenylethyl group (PYE)	0.00	0.52	1.85	0.80	1.91	0.76	3.54	1.53	3.66	1.45
COSMOSIL 5PBr	Pentabromophenyl group (PBr)	0.04	0.71	2.37	1.03	3.67	0.91	3.34	1.45	5.19	1.29
COSMOSIL 5PFP	Pentafluorophenyl group (PFP)	0.04	0.15	0.46	0.18	0.42	0.20	3.01	1.19	2.73	1.29
COSMOSIL 5NPE	Nitrophenylethyl group (NPE)	0.00	0.50	2.36	0.62	1.27	0.62	4.70	1.23	2.54	1.23
COSMOSIL 5C₁₈-MS-II	Monomeric octadecyl group (C₁₈-M)	0.17	0.17	0.16	0.25	0.46	0.17	0.98	1.51	2.76	1.04
COSMOSIL 5C₁₈-AR-II	Polymeric octadecyl group (C₁₈-P)	0.16	0.23	0.25	0.29	0.66	0.21	1.09	1.26	2.87	0.93
COSMOSIL 5Cholester	Cholesteryl group (CHO)	0.14	0.39	0.91	0.53	1.43	0.31	2.36	1.37	3.71	0.79

Mobile phase: ethanol/CO₂ = 5/95, (1) Hydrophilic interaction: separation factor (α) of solutes 9/8, (2) Hydrophobic interaction: α of solutes 10/8, (3) π-π interaction: α of solutes 11/8, (4) Dispersion interaction: α of solutes 12/8.