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Scheme of the epigenetic processes implicated in Neural Crest Cells (NCCs) and Enteric Nervous System (ENS) development in HSCR context. Epigenetic mechanisms identified in NCC development (A) and in ENS formation (B) with a possible role in the onset of the disease. Adapted from http://www.columbia.edu/itc/hs/medical/humandev/2006/HD10/ENS6.pdf.
