Table 3.

Safety data of excipients used in paediatric modified release preparation [10,68].

Excipient		Paediatric Safety Data Use	Main Function in Formulation
Cellulos derivatives	cellulose acetate	NA *	MR
	cellulose acetate phthalate	NA *	MR
	carmellose sodium	yes	suspending agent
	ethylcellulose	yes	MR taste masking
	hypromellose	yes	suspending agent MR taste masking
	methylcellulose	yes	suspending agent
ion exchange resin		NA *	drug/polymer complexation
methacrylic acid copolymers		NA *	MR
sodium polystyrene sulfate		NA *	drug/polymer complexation MR
sodium alginate		NA *	MR
calcium sulfate		NA *	MR
lauryl sulfate		NA *	MR
polyvinyl alcohol		NA *	MR

* NA: no data available.