Figure 1.

Genes in network proximity to the core genes of autism spectrum disorders (ASDs). (A) Diffusion score (Xs) normalized by its empirical p-value (horizontal axis) and number of interactions (|I|, vertical axis); only genes with p < 0.05 are shown. (B) Connected components of “core+13” network. (A,B) Blue points: 13 genes of “core+13”; pink points: core genes; yellow points: Significant genes outside “core+13” genes; red border of points: Genes supported at transcriptomic and/or epigenetic levels.