Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 9;20(13):3365. doi: 10.3390/ijms20133365

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Multi-system involvement in Myotonic Dystrophy types 1 and 2 (DM1 and DM2). Several tissue systems are shown with associated phenotypes together with proposed RNA mis-processing events. These events include: chloride voltage-gated channel 1 (CLCN1) exon (e)7A [81,82,83], calcium voltage-gated channel subunit alpha1 S (CACNA1S) e29 [84], bridging integrator 1 (BIN1) e11 [85], dystrophin (DMD) e78 [86], ryanodine receptor 1 (RYR1) e70 [87], pyruvate kinase isozymes M1/M2 (PKM1/M2) e10 [88], sodium voltage-gated channel alpha subunit 5 (SCN5A) e6 [89,90], troponin T2, cardiac type (TNNT2) e5 [91], microtubule associated protein tau (MAPT) e2, e3, e10 [92,93], insulin receptor (INSR) e11 [94,95] and microRNA-1 (miR-1) [96].