Figure 4.

Patterns of connectivity in non-spiking high density EEG (24). Left: comparison between healthy controls, left temporal lobe epilepsy and right temporal lobe epilepsy (20 subjects in each group). In controls, posterior cingulate and medial temporal structures are strong drivers of the network, the maximum being in the posterior cingulate cortex. In patients, there is a global reduction of the drivers with the maximum located in the ipsilateral medial temporal structures at group level. Right: the use of machine learning (two random forest classifiers) allowed achieving very high accuracy for the prediction of individual subjects suggesting a role of this analysis as a biomarker (71). Permission for reuse granted by John Wiley and Sons (License Number 4518770257321).