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Metabolomic and Lipidomic profiles of kidney in NHPs pre and post-irradiation. Panel A: Three dimensional PLS-DA plot showing separation of healthy NHPs (N = 8) from those who either survived (N = 18) or succumbed to radiation-induced (N = 14) tissue injury within 60 days.Prediction accuracy for 100 permutations yielded a p-value of 0.07. Panels B and C: the relative abundance of significantly dysregulated metabolites and lipids in the threes study groups, respectively.
