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. 2019 Jul 3;20(13):3273. doi: 10.3390/ijms20133273

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Expressions of NMDA receptor subunits in the frontal cortex from both hemispheres in young adult and old rats exposed to chronic sleep deprivation. Summary histograms illustrating the expressional changes in NR1 (A), NR2A (B) and NR2B (C) subunits. The optical density of samples of respective NMDA subunit bands was related to that of α-tubulin, results are presented as means ± SEM. Statistical significance (Student’s t-test) was calculated with respect to young adult controls (*** p < 0.001). SD—sleep deprivation, YCTRL—young adult controls (n = 12), YSD—young adult rats exposed to chronic SD (n = 12), OCTRL—old controls (n = 12), OSD—old rats exposed to chronic SD (n = 12).