Comparison of activities of NO synthases in the right and left parietal cortex of young adult and old rats exposed to chronic sleep deprivation (experiment III). Summary histogram of activities of NOS isoforms (A–C) expressed as nmoles/30 min/mg of proteins. Results are presented as means ± SEM. Statistical significance (Student’s t-test) was calculated with respect to young adult controls (* p < 0.05, ** p < 0.01). RH—right hemisphere, LH—left hemisphere, nNOS—neuronal NOS, eNOS—endothelial NOS, iNOS—inducible NOS, SD—sleep deprivation, YCTRL—young adult controls (n = 12), YSD—young adult rats exposed to chronic SD (n = 12), OCTRL—old controls (n = 12), OSD—old rats exposed to chronic SD (n = 12).