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. 2019 Jul 5;20(13):3310. doi: 10.3390/ijms20133310

Table 1.

The categories and characteristics of macrophages.

Categories Characteristics
Tissue-resident macrophages

  1. During embryonic organogenesis, they derive from yolk sac and fetal liver precursors [8].

  2. After birth, bone marrow or spleen-derived monocytes can replenish [9].

  3. They show specialized properties and functions to the tissue [9].
Infiltrating macrophages

  1. They derive from circulating monocytes [10].

  2. They present mainly two types of properties M1 and M2 subtypes [10].

  3. M1 is induced by Th1 cytokines and acts in the inflammatory response and antitumor immunity [11].

  4. M2 is induced by Th2 cytokines and acts in the anti-inflammatory and pro-tumorigenic activities [11].

The table above shows the categories of macrophages and their characteristics respectively.