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Anti-cadherin RGD antibodies as a potential therapeutic strategy against metastasis. Schematic representation of the activity of two anti-cadherin RGD monoclonal antibodies, showing their specificities against RGD motifs in cadherins. The antibodies can inhibit the interaction of the RGD motifs with the integrins, blocking their activation, signaling and consequently, the metastatic behavior of cancer cells.
