Table 1.
Clinical characteristics of RPL patients and controls.
| Characteristic | Controls (n = 236) | RPL Patients (n = 378) | p |
|---|---|---|---|
| Age (years) | 33.37 ± 5.81 | 33.24 ± 4.59 | 0.756 |
| BMI (kg/m²) | 21.69 ± 3.37 | 21.49 ± 3.87 | 0.642 |
| Previous pregnancy losses (N) | None | 3.29 ± 1.85 | |
| RPL < 14 wk (%) | None | 98.90% | |
| Live births (N) | 1.72 ± 0.72 | None | |
| Mean gestational age (weeks) | 39.26 ± 1.66 | 7.38 ± 1.92 | <0.0001 |
| PLT (103/μL) | 237.25 ± 66.19 | 255.43 ± 59.22 | 0.007 |
| Hct (%) | 35.63 ± 4.31 | 37.33 ± 3.37 | <0.0001 |
| LH (mIU/mL) | 3.32 ± 1.74 | 6.33 ± 12.21 | 0.011 |
| E2 (pg/mL) | 26.00 ± 14.75 | 35.78 ± 29.64 | 0.002 |
| Homocysteine (μmol/L) | NA | 6.94 ± 2.05 | |
| Folate (ng/mL) | NA | 14.27 ± 12.00 | |
| Total cholesterol (mg/dL) | NA | 187.80 ± 49.42 | |
| Uric acid (mg/dL) | NA | 3.77 ± 0.80 | |
| CD56+ NK cells (%) | NA | 18.10 ± 7.90 | |
| PAI-1 (ng/mL) | NA | 10.37 ± 5.70 | |
| PT (sec) | 11.51 ± 3.13 | 11.59 ± 0.86 | 0.727 |
| aPTT (sec) | 33.41 ± 3.74 | 32.32 ± 4.31 | 0.069 |
| BUN (mg/dL) | NA | 9.95 ± 2.79 | |
| Creatinine (mg/dL) | NA | 0.72 ± 0.12 | |
| FBS (mg/dL) | NA | 95.19 ± 17.15 | |
| HDL (mg/dL) | NA | 61.82 ± 17.63 | |
| TG (mg/dL) | NA | 175.79 ± 150.23 | |
| FSH (mIU/mL) | 8.12 ± 2.85 | 7.53 ± 10.63 | 0.566 |
| Prolactin (ng/mL) | NA | 15.57 ± 13.01 |
Abbreviations: RPL, recurrent pregnancy loss; BMI, body mass index; NA, not applicable; PAI-1, plasminogen activator inhibitor-1; PLT, platelet; PT, prothrombin time; aPTT, activated partial thromboplastin time; BUN, blood urea nitrogen; FSH, follicle-stimulating hormone; E2, prostaglandin E2; LH, luteinizing hormone; Hct, hematocrit; Hcy, homocysteine; TG, triglyceride; HDL, high-density lipoprotein; FBS, fasting blood glucose.