Table 4.
Characteristics | TP53+ or TP53-, FLT3+, RET- n = 16 | Other Mutational Status n = 19 | p-Value |
---|---|---|---|
Male/female, n (%) | 2/14 (12.5%/87.5%) | 2/17 (10.5%/89.5%) | 1.0000 |
Median age at diagnosis, years (range) | 50 (27–81) | 56 (27–82) | 0.4560 |
Age group (≤60 years/>60 years), n (%) | 3/13 (18.75%/81.25%) | 7/12 (36.8%/63.2%) | 0.2853 |
Median length of follow-up, months (range) | 108 (17–130) | 116 (28–144) | 0.5674 |
Multifocality, n (%) | 2 (12.5%) | 2 (10.5%) | 1.0000 |
Capsule invasion, n (%) | 5 (31) | 9 (47) | 0.3322 |
Extracapsular extension, n (%) | 9 (56.3%) | 9 (47.4%) | 0.6005 |
Nodal (N) involvement, n (%) | 1 (6.3%) | 3 (15.8%) | 0.6081 |
Mean tumor size, mm (range) | 32 (7–75) | 29 (12–18) | 0.6737 |
Tumor diameter ≤10 mm, n (%) | 1 (6.3%) | 1 (5.3%) | 1.0000 |
Localization in the right/left/both lobes, n (%) | 7/2/7 (43.8%/12.5%/43.8%) | 10/1/8 (52.6%/5.3%/42.1%) | 0.8844 |
Chronic lymphocytic thyroiditis n (%) | 2 (12.5%) | 5 (26.3%) | 0.4150 |
Radioactive iodine-refractoriness n (%) | 0 (0.0%) | 2 (10.5%) | 0.4891 |
The p-values were based on chi-square test (or Fisher’s exact test when appropriate) for categorical variables and Mann–Whitney U test for quantitative variables.