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. 2019 Jun 26;20(13):3126. doi: 10.3390/ijms20133126

Table 4.

The characteristics of patients diagnosed with follicular thyroid cancer according to their mutational status.

Characteristics TP53+ or TP53-, FLT3+, RET- n = 16 Other Mutational Status n = 19 p-Value
Male/female, n (%) 2/14 (12.5%/87.5%) 2/17 (10.5%/89.5%) 1.0000
Median age at diagnosis, years (range) 50 (27–81) 56 (27–82) 0.4560
Age group (≤60 years/>60 years), n (%) 3/13 (18.75%/81.25%) 7/12 (36.8%/63.2%) 0.2853
Median length of follow-up, months (range) 108 (17–130) 116 (28–144) 0.5674
Multifocality, n (%) 2 (12.5%) 2 (10.5%) 1.0000
Capsule invasion, n (%) 5 (31) 9 (47) 0.3322
Extracapsular extension, n (%) 9 (56.3%) 9 (47.4%) 0.6005
Nodal (N) involvement, n (%) 1 (6.3%) 3 (15.8%) 0.6081
Mean tumor size, mm (range) 32 (7–75) 29 (12–18) 0.6737
Tumor diameter ≤10 mm, n (%) 1 (6.3%) 1 (5.3%) 1.0000
Localization in the right/left/both lobes, n (%) 7/2/7 (43.8%/12.5%/43.8%) 10/1/8 (52.6%/5.3%/42.1%) 0.8844
Chronic lymphocytic thyroiditis n (%) 2 (12.5%) 5 (26.3%) 0.4150
Radioactive iodine-refractoriness n (%) 0 (0.0%) 2 (10.5%) 0.4891

The p-values were based on chi-square test (or Fisher’s exact test when appropriate) for categorical variables and Mann–Whitney U test for quantitative variables.