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. 2019 Jun 29;20(13):3192. doi: 10.3390/ijms20133192

Figure 4.

Figure 4

The effect of PP13 on the various layers of blood vessels. PP13 acts on the endothelial layer of the blood vessels and causes vasodilation by muscle relaxation through the signaling pathways of eNOS and prostaglandin 2. Further, PP13 causes stabilization of the surrounding connective tissues. Molecularly, this process requires the carbohydrate recognition domain to cross link between PP13 and molecules on the surface of the connective tissue and extracellular matrix.