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. 2019 Jun 29;20(13):3192. doi: 10.3390/ijms20133192

Table 1.

Placental galectins in primates.

Species Gal 10
Eosinophils
Gal 13
Placenta
Gal 14
Placenta
Gal 16
Placenta
Gal 17
Placenta
Gal 20
Placenta
Count Invasion Level
Chimpanzee 2 3+
Orangutan 10A 17C 4 2+
Baboon 1 1+
Human 10A 17A
17B
5 (with 2 subtypes of Gal 17) 4+
Gorilla 1 3+
Colobus 1 1+
Macaque 17C 4 2+
Marmoset 10A
10B
10C
4 (with 3 subtypes of Gal 10) 2+
Sp. Monkeys 10A
10B
10C
4 (with 3 subtypes of Gal 10) 2+
Total species # 4 8 5 4 3 2

The presence of placental galectins in primate placenta is provided following the analysis of the evolutionary differentiation tree [31,32,36,39,115] with the exception of Galectin 10 (Gal 10) that is generated in bone-marrow but reaches the placenta via its expression in white blood cells. The letters A, B, and C reflect isoforms of the molecules. In terms of invasion: gorilla, chimpanzee, and human species have the deepest trophoblast invasion (3+ and 4+) reaching the inner myometrium [114,115,116,117,118,119,120]. The others have a much shallower implantation (1+ or 2+). The color code indicates in which species the Gal isoforms are expressed. The numbers in “total” refer to the numbers of species in which a specific Gal isoform is expressed. The numbers in “Count” refer to the numbers of Gal isoforms expressed in a given species.