Figure 1.

TNIIIA2 promotes the proliferation of glioblastoma multiforme (GBM) cells expressing relatively high quantities of platelet-derived growth factor (PDGF)-Rβ. (A) PDGF-Rβ expression in a variety of GBM cell lines assessed by western blotting. (B) and (C) Effects of TNIIIA2 on proliferation in GBM cells with relatively high (B) and low (C) levels of PDGF-Rβ expression. GBM cells were treated with TNIIIA2 for 2 days. The number of viable cells was evaluated by WST-8 assay. Data represent the mean ± standard deviation of triplicate determinations, ** p < 0.01; NS not significant.