| CRC | colorectal carcinoma |
| TME | tumor micro-environment |
| iNOS | inducible nitric oxide-synthase |
| VEGF | vascular endothelial growth factor |
| NF-κB | nuclear factor-kappaB |
| wtp53 | wild type p53 |
| S100BmAb | S100B monoclonal antibody |
| HEPES | 4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid, N-(2-hydroxyethyl) piperazine-N′-(2 ethanesulfonic acid) |
| HIF1α | hypoxia-inducible factor 1-alpha |
| mTOR | mammalian Target of Rapamycin |
| RAGE | receptor for advanced glycation end products |
| RAGEmAb | RAGE monoclonal antibody |
| BSA | bovine serum albumin |
| MDPI | Multidisciplinary Digital Publishing Institute |
| DOAJ | Directory of open access journals |
| TLA | three letter acronym |
| LD | linear dichroism |